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Bipolar Headlines
Off-Label Use Of Antipsychotic Medications
Reducing the non-FDA-approved use of antipsychotic drugs may be a way to save money while having little effect on patient care, according to a Penn State College of Medicine study. Researchers say that 57.6 percent of patients prescribed antipsychotic medications in data from 2003 did not have schizophrenia or bipolar disorder, the conditions for which the drugs were approved for use...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday
New Genetic Findings: Gifts Of The MAGI In Schizophrenia And Bipolar Disorder
These findings are not about the classic story of gift-giving, although the MAGI genes (officially named membrane associated guanylate kinase, WW and PDZ domain containing proteins) do influence brain function in important ways. MAGI1 and MAGI2 are genes that code for the MAGI proteins...
Mon, 14 May 2012 00:00:00 PDT - Source:MedNewsToday
Brain Structure Affected By Psychiatric Medications
It is increasingly recognized that chronic psychotropic drug treatment may lead to structural remodeling of the brain...
Thu, 10 May 2012 00:00:00 PDT - Source:MedNewsToday
Broadening Bipolar Disorder Criteria Could Do More Harm Than Good For Patients
A Rhode Island Hospital psychiatrist and researcher explains the negative impact of broadening the diagnostic criteria for bipolar disorder in the upcoming Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). In a newly published commentary in the Journal of Clinical Psychiatry, Mark Zimmerman, M.D...
Thu, 26 Apr 2012 00:00:00 PDT - Source:MedNewsToday
2nd Generation Anti-Psychotic Drugs Publication Bias
According to a study published in PLoS Medicine, trials of second-generation anti-psychotic drugs, i.e. newer forms of medications for the treatment of psychotic illnesses like schizophrenia, that have been published in medical journals, may embellish their apparent clinical effectiveness. This selective reporting of trials is a phenomenon called publication bias...
Thu, 22 Mar 2012 02:00:00 PDT - Source:MedNewsToday
Circadian Rhythm May Hold Key For Treatment Of Bipolar Disorder
Scientists have gained insight into why lithium salts are effective at treating bipolar disorder in what could lead to more targeted therapies with fewer side-effects. Bipolar disorder is characterised by alternating states of elevated mood, or mania, and depression. It affects between 1% and 3% of the general population...
Thu, 15 Mar 2012 00:00:00 PDT - Source:MedNewsToday
Impulsive Behavior Regulated By Cannabinoid 2 Receptors
A new study lead by the Neuroscience Institute of Alicante reveals how manipulating the endocannabinoid system can modulate high levels of impulsivity. This is the main problem in psychiatric illnesses such a schizophrenia, bipolar disorder and substance abuse...
Sun, 11 Mar 2012 00:00:00 PDT - Source:MedNewsToday
Metabolic Side Effects Such As Obesity And Diabetes Caused By Antipsychotic Medications
In 2008, roughly 14.3 million Americans were taking antipsychotics - typically prescribed for bipolar disorder, schizophrenia, or a number of other behavioral disorders - making them among the most prescribed drugs in the U.S...
Fri, 03 Feb 2012 01:00:00 PDT - Source:MedNewsToday
New Study May End 2 Decades Of Suspicion: Does Borna Disease Virus Cause Mental Illness?
Over the past 30 years, numerous studies have linked Borna disease virus (BDV) with mental illnesses such as bipolar disorder, schizophrenia, anxiety disorder and dementia. Genetic fragments and antibodies to this RNA virus, which causes behavior disorders in a range of mammals and birds, have been found to be prevalent in psychiatric patients, but study results have been inconsistent...
Thu, 02 Feb 2012 00:00:00 PDT - Source:MedNewsToday
Lithium For Bipolar Disorder - Pros And Cons Unclear
The most effective long-term treatment for bipolar disorder is lithium. It offers protection against depression and mania and reduces the risk of suicide and short-term mortality. However, according to a study in The Lancet ,safety concerns have made the use of lithium controversial...
Mon, 23 Jan 2012 10:00:00 PDT - Source:MedNewsToday
Link Between PCE In Drinking Water And An Increased Risk Of Mental Illness
PCE in drinking water linked to an increased risk of mental illness The solvent tetrachloroethylene (PCE) widely used in industry and to dry clean clothes is a neurotoxin known to cause mood changes, anxiety, and depression in people who work with it...
Sun, 22 Jan 2012 00:00:00 PDT - Source:MedNewsToday
Improvements In Unipolar And Bipolar Depression Following Deep Brain Stimulation
A new study shows that deep brain stimulation (DBS) is a safe and effective intervention for treatment-resistant depression in patients with either unipolar major depressive disorder (MDD) or bipolar ll disorder (BP). The study was published Online First by Archives of General Psychiatry, one of the JAMA/Archives journals. The study was led by Helen S...
Tue, 03 Jan 2012 02:00:00 PDT - Source:MedNewsToday
Rare Genetic Mutations Linked To Bipolar Disorder
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder. The findings were published in the Dec. 22 issue of the journal Neuron...
Mon, 02 Jan 2012 00:00:00 PDT - Source:MedNewsToday
Link Between Opioid Abuse And Mood And Anxiety Disorders
Individuals suffering from mood and anxiety disorders such as bipolar, panic disorder and major depressive disorder may be more likely to abuse opioids, according to a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health. They found that mood and anxiety disorders are highly associated with non-medical prescription opioid use...
Sun, 25 Dec 2011 00:00:00 PDT - Source:MedNewsToday
Rare Deletions Or Duplications Of DNA Tied To Bipolar Disorder
New research led by University of California, San Diego (UCSD) School of Medicine, finds that rare copy number variants (CNVs) where sections of DNA are either duplicated or missing, seem to play a key role in the risk for early onset bipolar disorder, which appears in childhood or early adulthood...
Fri, 23 Dec 2011 00:00:00 PDT - Source:MedNewsToday
Endophenotype Strategies For The Study Of Neuropsychiatric Disorders
The identification of genes that contribute to a susceptibility to complex neuropsychiatric disorders such as schizophrenia, major depression and bipolar disorders has been not very successful using conventional genetic approach...
Tue, 20 Dec 2011 00:00:00 PDT - Source:MedNewsToday
Post-Partum Psychiatric Problems Increase Risk Of Bipolar Disorder
A report published by Archives of General Psychiatry, one of the JAMA/Archives journals, shows mothers experiencing a psychiatric episode in the first 30 days post-partum appear to have an increased risk of developing bipolar affective disorder...
Tue, 06 Dec 2011 00:00:00 PDT - Source:MedNewsToday
Missing Synapse Protein Linked To Abnormal Behaviors
Although many mental illnesses are uniquely human, animals sometimes exhibit abnormal behaviors similar to those seen in humans with psychological disorders. Such behaviors are called endophenotypes...
Sun, 27 Nov 2011 00:00:00 PDT - Source:MedNewsToday
Schizophrenia Gene Associated With Psychiatric Disorders And Brain Development
Significant progress has been made in understanding the genetic risk factors underlying psychiatric disease. Recent studies have identified common genetic mutations conferring modest risk and rare variants comprising significant risk...
Sun, 20 Nov 2011 00:00:00 PDT - Source:MedNewsToday
How Schizophrenia Gene Linked To Psychiatric Disorders Impairs Brain Development
Researchers have discovered how the gene variant DISC1, which is linked to schizophrenia and other psychiatric disorders, impairs a particular signalling pathway in neurons that is crucial for normal brain development. Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, and colleagues, write about their findings in the 17 November issue of the journal Neuron...
Fri, 18 Nov 2011 02:00:00 PDT - Source:MedNewsToday
Potential To Predict Outcome Of Psychotic Episodes Using Brain Scans
Computer analysis of brain scans could help predict how severe the future illness course of a patient with psychosis will be, according to research funded by the Medical Research Council and the Wellcome Trust. The findings could allow doctors to make more accurate decisions about how best to treat patients...
Wed, 09 Nov 2011 00:00:00 PDT - Source:MedNewsToday
Diagnosis Of Bipolar Disorder Improved By Specific Criteria
Use of criteria such as family history of mania and early onset of illness resulted in the diagnosis of 31 percent more cases of bipolar disorder in individuals experiencing a major depressive episode, according to results of a large international study reported this year. Charles L. Bowden, M.D...
Wed, 09 Nov 2011 00:00:00 PDT - Source:MedNewsToday
Drug Development Process Could Be Simplified By Chemical Breakthrough
A new chemical process developed by a team of Harvard researchers greatly increases the utility of Positron Emission Tomography (PET) in creating real-time 3-D images of chemical process occurring inside the human body...
Mon, 07 Nov 2011 00:00:00 PDT - Source:MedNewsToday
High Blood Pressure May Lead To Missed Emotional Cues
Your ability to recognize emotional content in faces and texts is linked to your blood pressure, according to a Clemson University researcher. A recently published study by Clemson University psychology professor James A. McCubbin and colleagues has shown that people with higher blood pressure have reduced ability to recognize angry, fearful, sad and happy faces and text passages...
Sun, 06 Nov 2011 00:00:00 PDT - Source:MedNewsToday
Gene Regulatory Protein Is Reduced In Bipolar Disorder
Low levels of a brain protein that regulates gene expression may play a role in the origin of bipolar disorder, a complex and sometimes disabling psychiatric disease...
Thu, 27 Oct 2011 00:00:00 PDT - Source:MedNewsToday
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